Photodynamic Therapy and Cytoluminescent Therapy
The idea of photodynamic therapy is basically quite simple and has been known for more than a century. Neils Finsen even won a Nobel Prize for his light therapy, and Hermann von Tappeier published his work in 1904. But it was not until the 1960s when laser research was being advanced that people remembered this work. The idea however stayed the same. (Cancer) cells are enriched with a dye and then these cells are radiated with light. Enrichment can occur through salves (aminolevulinic acid) or through orally administered photosentizers.
But what sounds so ingenuous in theory, unfortunately is anything but a successful cancer therapy. Determining the correct photosensitizer in combination with the right wavelength, or the determination of which light is even the proper light, will continue to provide issues for discussion in the future. Although there have been frequent smaller studies for different types of cancer, which seemed entirely hopeful, to this point no team has been successful in producing significantly better chances for survival. And this will never happen, because the therapy focuses on fast destruction of the tumor.
Even cytoluminescent therapy which was so highly praised in 2002, and which was used intensively first in Ireland, and then even in a clinic in Germany, has proven itself to be anything other than successful. In this therapy a fast-acting photosensitizer (photoflora) is used with the promise that it better and more quickly enriches in cancer cells. Not only the fact that both clinics today distance themselves from the therapy, even all of the great promises have quickly dissolved into thin air, and in 2005 there are not very many people talking about this therapy.
Personal opinion: I believe that the photodynamic therapy has a future as a selectively effective therapy for fast tumor destruction. Even if we are quite far the goal today, this could certainly be an area of considerable progress in the future. However I discount some of the extravagant promises which do not have the well-being of the patient in mind.